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Deputy Director of the CEBM, GP and clinical lecturer at the University of Oxford.

Cardiology trainee and clinical research fellow at the University of Oxford

See Carl Heneghan in action in the CEBM's workshop videos.
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We first criticized this drug in 2006, when in the BMJ we first mooted rosiglitazone in the DREAM trial – which cost $23million - caused a significant increase in heart failure, despite the population being at low risk of such a problem. The drug showed no clear benefit at 3 years on clinical outcomes and the rate of all cardiovascular events tended to be higher in the treatment group.
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