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Deputy Director of the CEBM, GP and clinical lecturer at the University of Oxford.

Cardiology trainee and clinical research fellow at the University of Oxford

See Carl Heneghan in action in the CEBM's workshop videos.
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At the European Society for Cardiology Congress this week, we learned about more situations where aspirin is unhelpful. Professor Gerry Fowkes and colleagues from Edinburgh looked at nearly 30000 men and women aged 50 to 80 years who had never had any cardiovascular disease, but had a low ankle-brachial pressure index, a marker of peripheral vascular disease.
Since medical school, I have always been struck by the number of patients of all ages who live life by the “aspirin-a-day” mantra. In people who have had heart attacks or strokes, aspirin reduces further events by 25%. This beneficial effect is known as “secondary prevention”, and outweighs aspirin’s bleeding risk [1, 2].
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