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Carl Heneghan

Carl Heneghan

Deputy Director of the CEBM, GP and clinical lecturer at the University of Oxford.

Ami Banerjee

Ami Banerjee

Cardiology trainee and clinical research fellow at the University of Oxford

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confidence interval

14th November 2009 03:32am

Understanding evidence-based medicine in 4 days. Lesson 2: 5% is the magic number for confidence and certainty.   Ami Banerjee

Some things in life are certain. We are 100% sure that every human being will die at some point in their lifetime. Other things are close to 100% certain, but there is a small chance of an alternative outcome. When a person has a coronary angiogram to look at the arteries in their heart, we are 99.9% certain that they will have an uneventful procedure, but 0.1% of the time there will be a major complication such as bleeding, stroke, or a heart attack. If the person has had previous heart attacks or other illnesses, this chance increases and might reach as much as 2%.

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